{"product_id":"rat-secreted-phosphoprotein-24-spp2-elisa-kit-bhe13700284","title":"Rat Secreted phosphoprotein 24 (SPP2) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRat Secreted phosphoprotein 24 (SPP2) ELISA Kit has high sensitivity and excellent specificity for detection of Rat SPP2. No significant cross-reactivity or interference between Rat SPP2 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eSphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P.The deduced 399-amino acid protein has a calculated molecular mass of 44.7 kD and shares 39.3% amino acid identity with SGPP1. SGPP2 has an N-terminal hydrophobic region, 3 conserved phosphatase-family motifs, and is predicted to be an integral membrane protein with as many as 9 membrane-spanning segments. Immunofluorescence microscopy showed a reticular staining pattern in the perinuclear and cytosolic regions of HEK293 cells, and SGPP2 colocalized with an endoplasmic reticulum antibody. Northern blot analysis of human tissues detected a 5.1-kb transcript with high expression in kidney and heart, followed by brain, colon, lung, and small intestine.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338585039213,"sku":"KTE100125-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338669810029,"sku":"KTE100125-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338669842797,"sku":"KTE100125-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338669875565,"sku":"KTE100125-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/KTE100125.png?v=1778954611","url":"https:\/\/www.ebiohippo.com\/products\/rat-secreted-phosphoprotein-24-spp2-elisa-kit-bhe13700284","provider":"BioHippo","version":"1.0","type":"link"}