{"product_id":"rat-transitional-endoplasmic-reticulum-atpase-vcp-elisa-kit-bhe13700164","title":"Rat Transitional endoplasmic reticulum ATPase (VCP) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRat Transitional endoplasmic reticulum ATPase (VCP) ELISA Kit has high sensitivity and excellent specificity for detection of Rat VCP. No significant cross-reactivity or interference between Rat VCP and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eThe deduced protein contains 1,236 amino acids. RT-PCR ELISA detected moderate VCPIP1 expression in all adult and fetal tissues examined.Reassembly of the Golgi apparatus from membrane fragments after cell division requires the ATPases NSF and p97 (VCP), as well as the cofactor p47 (NSFL1C) and the receptor syntaxin-5 (STX5A). rat Vcip135 was essential for p97\/p47-mediated membrane fusion and that Vcip135 bound to the p97\/p47\/Stx5a complex and dissociated it via p97-catalyzed ATP hydrolysis. Microinjection of antibodies against Vcip135 and p47 in rat kidney cells showed that Vcip135 and p47 were required for Golgi and endoplasmic reticulum assembly.a cycle of ubiquitination and VCIP135-mediated deubiquitination regulates Golgi membrane dynamics during mitosis.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338581074285,"sku":"KTE100015-48T","price":339.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338675446125,"sku":"KTE100015-96T","price":589.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338675478893,"sku":"KTE100015-96TX5","price":2629.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338675511661,"sku":"KTE100015-96TX50","price":24569.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/rat-transitional-endoplasmic-reticulum-atpase-vcp-elisa-kit-bhe13700164","provider":"BioHippo","version":"1.0","type":"link"}