{"product_id":"rat-vitamin-k1-vk1-elisa-kit-bhe13700157","title":"Rat Vitamin K1 (VK1) ELISA Kit","description":"\u003cp\u003e\u003cb\u003eFeatures \u0026amp; Benefits\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eRat Vitamin K1 (VK1) ELISA Kit has high sensitivity and excellent specificity for detection of Rat VK1. No significant cross-reactivity or interference between Rat VK1 and analogues was observed.\u003c\/p\u003e\u003cp\u003e\u003cb\u003eBackground\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003eVitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins.\u003c\/p\u003e\u003cp\u003eVKORC1 is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.\u003c\/p\u003e","brand":"Abbkine Scientific Co., Ltd.","offers":[{"title":"48 T","offer_id":53338584220013,"sku":"KTE100008-48T","price":359.0,"currency_code":"USD","in_stock":true},{"title":"96 T","offer_id":53338676232557,"sku":"KTE100008-96T","price":619.0,"currency_code":"USD","in_stock":true},{"title":"96 T×5","offer_id":53338676265325,"sku":"KTE100008-96TX5","price":2809.0,"currency_code":"USD","in_stock":true},{"title":"96 T×50","offer_id":53338676298093,"sku":"KTE100008-96TX50","price":26209.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/rat-vitamin-k1-vk1-elisa-kit-bhe13700157","provider":"BioHippo","version":"1.0","type":"link"}