{"product_id":"recombinant-chimeric-esat6-cfp10-bhp11006097","title":"Recombinant Chimeric ESAT6-CFP10","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Chimeric ESAT6-CFP10\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eMycobacterium antigen ESAT6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate (ST-CF) and it can easily be detected in tuberculosis patients. The export of ESAT-6 which is a potent T-cell antigen, and related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands and there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host. This antigen includes many epitopes detectable in the serum of most patients with tuberculosis (more than 90%). By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide and monophosphoryllipide. ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection and BCG vaccination. The main topic in ESAT-6 using is in antibody production and in test-systems for tuberculosis elaboration. Early secretory antigen 6 (ESAT6) and cell filtrate protein 10 (CFP10) are 2 antigens secreted as a complex by the replicating Mycobacterium tuberculosis complex (MTC).\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"100 ug","offer_id":53038182203757,"sku":"pro-2737-100UG","price":165.0,"currency_code":"USD","in_stock":true},{"title":"0.5 mg","offer_id":53038547730797,"sku":"pro-2737-05MG","price":660.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038547763565,"sku":"pro-2737-1MG","price":1320.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-esat6-cfp10-PRO-2737.png?v=1782158394","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-chimeric-esat6-cfp10-bhp11006097","provider":"BioHippo","version":"1.0","type":"link"}