{"product_id":"recombinant-cholera-toxin-b-subunit-bhp11006085","title":"Recombinant Cholera Toxin B subunit","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Cholera Toxin B subunit\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCholera Toxin B subunit (ctxB) Cholera is a protein complex secreted by the bacterium Vibrio cholerae. ctxB is responsible for the massive, watery diarrhea characteristic of cholera infection. The cholera toxin is an oligomeric complex made up of 6 protein subunits: a single copy of the A subunit and5 copies of the B subunit, denoted as AB5. Subunit B binds while subunit A activates the G protein which activates adenylate cyclase. The five B subunits form a five-membered ring. The A subunit has 2 important segments. The A1 portion of the chain (CTA1) is a globular enzyme payload that ADP-ribosylates G proteins, while the A2 chain (CTA2) forms an extended alpha helix which sits snugly in the central pore of the B subunit ring.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"50 ug","offer_id":53038182039917,"sku":"pro-2605-50UG","price":90.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038544879981,"sku":"pro-2605-100UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038544912749,"sku":"pro-2605-1MG","price":880.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ctxb-protein-PRO-2605.png?v=1782158394","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-cholera-toxin-b-subunit-bhp11006085","provider":"BioHippo","version":"1.0","type":"link"}