{"product_id":"recombinant-hdr3-muig-bhp14700019","title":"Recombinant hDR3-muIg","description":"\u003cdiv class=\"bhp-desc\"\u003e\n\u003cstyle\u003e\n.bhp-desc{font-size:16px;color:#1a1a1a;line-height:1.7}\n.bhp-desc h2{font-size:18px;font-weight:700;color:#003366;margin:24px 0 10px;padding-bottom:6px;border-bottom:2px solid #003366}\n.bhp-desc p{margin:0 0 12px}\n.bhp-desc .bhp-spec-table{width:100%;border-collapse:collapse;margin:12px 0 18px}\n.bhp-desc .bhp-spec-table th{width:36%;text-align:left;padding:8px 12px;background:#e8f0fb;color:#003366;font-weight:600;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-spec-table td{padding:8px 12px;vertical-align:top;border:1px solid #ccd9f0}\n.bhp-desc .bhp-qc-badge{display:inline-block;background:#e6f4ea;color:#1a7a3c;border:1px solid #a8d5b5;border-radius:4px;padding:6px 14px;font-size:14px;font-weight:600}\n.bhp-desc .bhp-warning-box{background:#fff8e6;border-left:4px solid #e6a817;padding:10px 14px;margin:10px 0 14px;border-radius:0 4px 4px 0}\n.bhp-desc .bhp-cat-pill{display:inline-block;background:#003366;color:#fff;border-radius:20px;padding:3px 12px;font-size:13px;margin-bottom:10px}\n\u003c\/style\u003e\n\n\u003ch2\u003eScientific Background\u003c\/h2\u003e\n\u003cp\u003eHuman DR3 (TRAMP, LARD) was redesignated TNF receptor superfamily member 25. TL1A is a ligand which can induce apoptosis through a cytoplasmic death domain similar to the CD178-CD95 (FasL-Fas) interaction. Alternatively, engagement of DR3 on T cells can synergize with other activating signals to enhance IFN g production.\u003c\/p\u003e\n\n\u003ch2\u003eProduct Description\u003c\/h2\u003e\n\u003cspan class=\"bhp-cat-pill\"\u003eCHO Cells\u003c\/span\u003e\n\u003cp\u003e\u003cstrong\u003eRecombinant hDR3-muIg\u003c\/strong\u003e is a recombinant human fusion protein produced in \u003cstrong\u003eCHO Cells\u003c\/strong\u003e cells. Molecular Structure: A soluble fusion protein combining the extracellular (150aa) domain of human DR3 and murine IgG2a Fc and hinge region (233aa), with a predicted monomeric molecular weight of 42.9 kd.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAlternative names:\u003c\/strong\u003e TRAMP, LARD, TNFRSF25\u003c\/p\u003e\n\n\u003ch2\u003eProtein Specifications\u003c\/h2\u003e\n\u003ctable class=\"bhp-spec-table\"\u003e\n  \u003ctr\u003e\n\u003cth\u003eFusion Format\u003c\/th\u003e\n\u003ctd\u003eMurine IgG Fc Fusion (muIg)\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eExpression System\u003c\/th\u003e\n\u003ctd\u003eCHO Cells\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eMolecular Weight\u003c\/th\u003e\n\u003ctd\u003e42.9 kDa\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eFormulation\u003c\/th\u003e\n\u003ctd\u003e50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eStorage\u003c\/th\u003e\n\u003ctd\u003eStore at 2 - 5°C. Freeze\/Thawing is not recommended.\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eSpecies Reactivity\u003c\/th\u003e\n\u003ctd\u003eHuman\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eValidated Applications\u003c\/th\u003e\n\u003ctd\u003eELISA\u003c\/td\u003e\n\u003c\/tr\u003e\n  \u003ctr\u003e\n\u003cth\u003eAvailable Conjugates\u003c\/th\u003e\n\u003ctd\u003eBiotin, Unconjugated\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cspan class=\"bhp-qc-badge\"\u003e✔ Research Use Only (RUO)\u003c\/span\u003e\u003c\/p\u003e\n\n\u003ch2\u003eSafety \u0026amp; Handling\u003c\/h2\u003e\n\u003cdiv class=\"bhp-warning-box\"\u003e\n\u003cp\u003e\u003cstrong\u003eResearch Use Only.\u003c\/strong\u003e Not intended for diagnostic, therapeutic, or clinical use. Handle according to good laboratory practice (GLP). Consult the Safety Data Sheet (SDS) prior to use.\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003ch2\u003eRelated Products\u003c\/h2\u003e\n\u003cp\u003eBrowse our full collection of \u003ca href=\"\/collections\/proteins\"\u003erecombinant proteins\u003c\/a\u003e and \u003ca href=\"\/collections\/antibodies\"\u003eantibodies\u003c\/a\u003e for immunology and immune checkpoint research.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Ancell Corporation","offers":[{"title":"Purified (with Antibiotic) \/ 25 ug","offer_id":53339388379501,"sku":"528-020","price":420.0,"currency_code":"USD","in_stock":true},{"title":"Purified (Preservative-free) \/ 25 ug","offer_id":53339390902637,"sku":"528-820","price":420.0,"currency_code":"USD","in_stock":true},{"title":"Biotin conjugate \/ 25 ug","offer_id":53339390935405,"sku":"528-030","price":510.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/recombinant-hdr3-muig-bhp14700019","provider":"BioHippo","version":"1.0","type":"link"}