{"product_id":"recombinant-human-alpha-1-antitrypsin-active-bhp11004850","title":"Recombinant Human Alpha-1 Antitrypsin, Active","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Alpha-1 Antitrypsin, Active\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eSERPINA1 is secreted and is a serine protease inhibitor which its targets include elastase, plasmin, collagenase, leucocytic proteases, trypsin, chymotrypsin, and plasminogen activator. Defects in SERPINA1 gene can cause emphysema or liver disease. SERPINA1 is an endogenous inhibitor of serine proteases and inhibits the catalytic domain of human recombinant matriptase in vitro. Rise in SERPINA1 occurs as an acute phase response to tissue necrosis and inflammation. mutations in SERPINA1 and SLC11A1 genes change the balance between elastase produced by leukocytes during phagocytosis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"20 ug","offer_id":53038159528301,"sku":"pro-907-20UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038498152813,"sku":"pro-907-100UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038498185581,"sku":"pro-907-1MG","price":1050.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-alpha-1-antitrypsin-active-bhp11004850","provider":"BioHippo","version":"1.0","type":"link"}