{"product_id":"recombinant-human-c-type-lectin-domain-family-5-member-a-sf9-bhp11005787","title":"Recombinant Human C-Type Lectin Domain Family 5, Member A, Sf9","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human C-Type Lectin Domain Family 5, Member A, Sf9\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eC-type lectin domain family 5-member A isoform 1 (CLEC5A) is part of the CTL\/CTLD superfamily which carry various functions, for instance cell-cell signaling, cell adhesion, glycoprotein turnover, in addition to their inflammation \u0026amp; immune response abilities. CLEC5A operates as a cell attachment receptor for all 4 serotypes of Dengue virus in addition to Japanese encephalitis virus. CLEC5A binds to the dengue virus and it triggers signaling through the phosphylation of TYROBP, as a result no viral entrance occurs, however this interaction does stimulate proinflammatory cytokine release. CLEC5A preforms as a positive regulator of osteoclastogenesis and also a main regulator of synovial injury \u0026amp; bone erosion for the period of autoimmune joint inflammation.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038174634349,"sku":"pro-2554-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038527185261,"sku":"pro-2554-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038527218029,"sku":"pro-2554-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-clec5a-PRO-2554.png?v=1782158378","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-c-type-lectin-domain-family-5-member-a-sf9-bhp11005787","provider":"BioHippo","version":"1.0","type":"link"}