{"product_id":"recombinant-human-casein-kinase-2-alpha-1-bhp11000908","title":"Recombinant Human Casein Kinase 2 alpha 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Casein Kinase 2 alpha 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe Casein kinase 2 (EC2.7.11.1) is a serine\/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase\u003cbr\u003e2. Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eActivity \u0026amp; assay information\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnit Definition:\u003c\/strong\u003e No protease activity detectable, specific activity \u0026gt; 1.320 U\/mg (1U = 1µmol\/min at 37 degree C) using the synthetic peptide RRRDDDSDDD.\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"3 ug","offer_id":53038065680749,"sku":"pka-208-3UG","price":400.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038313374061,"sku":"pka-208-10UG","price":800.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038313406829,"sku":"pka-208-20UG","price":1500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-csnk2a1-human-PKA-208.png?v=1782158161","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-casein-kinase-2-alpha-1-bhp11000908","provider":"BioHippo","version":"1.0","type":"link"}