{"product_id":"recombinant-human-caspase-recruitment-domain-family-member-18-bhp11003024","title":"Recombinant Human Caspase Recruitment Domain Family, Member 18","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Caspase Recruitment Domain Family, Member 18\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCARD18 belongs to the death-domain-fold superfamily which is induced by proinflammatory stimuli. CARD18 contains basically only a Caspase recruitment domain, inhibits generation of IL-1b by cooperating with caspase-1 and inhibiting connotation with RIP\u003cbr\u003e2. The connotation of CARD18 to caspase-1 is enabled by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038099562861,"sku":"pro-1061-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038381760877,"sku":"pro-1061-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038381793645,"sku":"pro-1061-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-card18-human-PRO-1061.png?v=1782158232","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-caspase-recruitment-domain-family-member-18-bhp11003024","provider":"BioHippo","version":"1.0","type":"link"}