{"product_id":"recombinant-human-cyclin-dependent-kinase-inhibitor-1b-bhp11000950","title":"Recombinant Human Cyclin-Dependent Kinase Inhibitor 1B","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cyclin-Dependent Kinase Inhibitor 1B\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCyclin-dependent kinase inhibitor 1B (CDKN1B) is a member of the Cip\/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. The CDKN1B protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and so controls the cell cycle progression at G1. CDKN1B is often referred to as a cell cycle inhibitor protein since its major function is to stop or slow down the cell division cycle. The degradation of the CDKN1B protein, which is triggered by its CDK dependent phosphorylation and ensuing ubiquitination by SCF complexes, is compulsory for the cellular transition from inactive to the proliferative state.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038065942893,"sku":"pka-012-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038315274605,"sku":"pka-012-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038315307373,"sku":"pka-012-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cdkn1b-human-PKA-012.png?v=1782158161","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-cyclin-dependent-kinase-inhibitor-1b-bhp11000950","provider":"BioHippo","version":"1.0","type":"link"}