{"product_id":"recombinant-human-cytokeratin-8-his-tag-bhp11003213","title":"Recombinant Human Cytokeratin 8 His Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Cytokeratin 8 His Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCytokeratin 8 (KRT8) belongs to the type II keratin family clustered on the long arm of chromosome\u003cbr\u003e12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. KRT8 has a role in retaining cellular structural integrity and also functions in signal transduction and cellular differentiation. KRT8 gene mutations cause cryptogenic cirrhosis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038105919853,"sku":"pro-1567-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038392148333,"sku":"pro-1567-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038392181101,"sku":"pro-1567-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-krt8-human-his-PRO-1567.png?v=1782158245","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-cytokeratin-8-his-tag-bhp11003213","provider":"BioHippo","version":"1.0","type":"link"}