{"product_id":"recombinant-human-diamine-acetyltransferase-1-sat1-partial-bhp10507332","title":"Recombinant Human Diamine acetyltransferase 1 (SAT1), partial","description":"\u003ch2\u003eOverview\u003c\/h2\u003e\u003cp\u003eThis Recombinant Protein provides recombinant \u003cstrong\u003eSAT1\u003c\/strong\u003e from Homo sapiens (Human), produced in E.coli (region 5-171aa). It is commonly used as a defined reagent for assay development, binding studies, and mechanistic research (RUO).\u003c\/p\u003e\u003ch2\u003eKey elements and design rationale\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eRegion:\u003c\/strong\u003e 5-171aa (domain boundaries can affect binding\/activity readouts).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eExpression host:\u003c\/strong\u003e E.coli (may differ from native PTMs\/processing).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTag(s):\u003c\/strong\u003e His (supports purification\/detection; consider tag effects in controls).\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eBiological background\u003c\/h2\u003e\u003cp\u003eAlso reported as Polyamine N-acetyltransferase 1;Putrescine acetyltransferase;Spermidine\/spermine N(1)-acetyltransferase 1 ;SSAT ;SSAT-1. Enzyme which catalyzes the acetylation of polyamines. Substrate specificity.\u003c\/p\u003e\u003ch2\u003eResearch relevance and current trends\u003c\/h2\u003e\u003cul\u003e\u003cli\u003eUse of recombinant standards to improve assay calibration and cross-study comparability.\u003c\/li\u003e\u003c\/ul\u003e\u003cp\u003eEnzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine \u0026gt;\u0026gt; spermine \u0026gt; N(1)-acetylspermine \u0026gt; putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.\u003c\/p\u003e\u003ch2\u003eCommon research applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eStandard curve or spike-in reference for quantitative assays involving SAT1\u003c\/li\u003e\n\u003cli\u003eBinding and specificity benchmarking for detection reagents (conceptual)\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eNotes for experimental interpretation\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eRecombinant constructs may not capture all native isoforms or PTMs.\u003c\/li\u003e\n\u003cli\u003eConsider tag- or host-related effects when interpreting binding or activity.\u003c\/li\u003e\n\u003cli\u003eUse appropriate blanks and matrix\/control concepts to separate signal from background.\u003c\/li\u003e\n\u003c\/ul\u003e\u003c!-- Sources (internal): - UniProtKB P21673 — UniProt — https:\/\/www.uniprot.org\/uniprotkb\/P21673 - NCBI Gene search: SAT1 — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/gene\/?term=SAT1 - Ensembl search: SAT1 — Ensembl — https:\/\/www.ensembl.org\/Multi\/Search\/Results?q=SAT1 - Reactome Pathway Browser — Reactome — https:\/\/reactome.org\/ - NCBI Bookshelf — NCBI — https:\/\/www.ncbi.nlm.nih.gov\/books\/ --\u003e","brand":"CUSABIO TECHNOLOGY LLC","offers":[{"title":"1 mg","offer_id":53053409722733,"sku":"CSB-EP020717HU1a0-1MG","price":1812.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53053539909997,"sku":"CSB-EP020717HU1a0-100UG","price":419.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53053539942765,"sku":"CSB-EP020717HU1a0-20UG","price":224.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/CSB-RP027594h-SDS.jpg?v=1772177659","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-diamine-acetyltransferase-1-sat1-partial-bhp10507332","provider":"BioHippo","version":"1.0","type":"link"}