{"product_id":"recombinant-human-diphthamide-biosynthesis-2-bhp11004399","title":"Recombinant Human Diphthamide Biosynthesis 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Diphthamide Biosynthesis 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eDiphthamide biosynthesis protein 2 (DPH2) is a homodimer and each of its monomers can bind a [4Fe-4S] cluster. DPH2 is the target of ADP ribosylating diphtheria toxin (DT) and Pseudomonas exotoxin A (PE). DPH2 was identified by its ability to complement a diphthamide mutant strain, and thus serves in diphthamide biosynthesis. The loss of DPH2 pre-activates NF-kB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038145962349,"sku":"pro-2421-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038470365549,"sku":"pro-2421-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038470398317,"sku":"pro-2421-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-dph2-human-PRO-2421.png?v=1782158324","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-diphthamide-biosynthesis-2-bhp11004399","provider":"BioHippo","version":"1.0","type":"link"}