{"product_id":"recombinant-human-dnaj-hsp40-homolog-subfamily-b-member-8-bhp11003476","title":"Recombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 8","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human DnaJ (Hsp40) Homolog, Subfamily B, Member 8\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eDnaJ homolog subfamily B member 8 (DNAJB8) is superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins. DNAJB8 is a member of the DNAJ\/HSP40 family of proteins that regulate chaperone activity. DNAJB8 is (de)acetylated at 2 conserved C-terminal lysines which aren’t involved in substrate binding, but do have a role in suppressing protein aggregation. DNAJB8 has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038113456493,"sku":"hsp-050-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038408925549,"sku":"hsp-050-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038408958317,"sku":"hsp-050-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-dnajb8-human-HSP-050.png?v=1782158263","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-dnaj-hsp40-homolog-subfamily-b-member-8-bhp11003476","provider":"BioHippo","version":"1.0","type":"link"}