{"product_id":"recombinant-human-family-with-sequence-similarity-84-member-b-bhp11003362","title":"Recombinant Human Family with Sequence Similarity 84, Member B","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Family with Sequence Similarity 84, Member B\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eFamily with Sequence Similarity 84, Member B (FAM84B) coprecipitated with a downstream effector of RAS, CRAF. Binding of FAM83B with CRAF interrupted CRAF\/14-3-3 interactions and increased CRAF membrane localization, causing elevated MAPK and mammalian target of rapamycin (mTOR) signaling. FAM84B is an oncogene and possibly represents a new target for therapeutic intervention.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038108901741,"sku":"pro-1779-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038401585517,"sku":"pro-1779-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038401618285,"sku":"pro-1779-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-family-with-sequence-similarity-84-member-b-bhp11003362","provider":"BioHippo","version":"1.0","type":"link"}