{"product_id":"recombinant-human-fetuin-b-bhp11004064","title":"Recombinant Human Fetuin-B","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Fetuin-B\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eFetuin-B (FETUB) belongs to the fetuin family, part of the cystatin superfamily proteins and comprised of 2 cystatin domains. Fetuin-B is found in a secreted form in the serum, it is expressed in the liver, tongue and placenta. FETUB regulates osteogenesis by inhibition effect on mineralization. Fetuins are implicated in a number of various functions, including osteogenesis and bone resorption, regulation of the hepatocyte growth factor receptors, and response to systemic inflammation. FETUB also has a role in oocyte maturation. Fetuin-B is essential in preventing premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, which is a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038134395245,"sku":"pro-1586-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038448476525,"sku":"pro-1586-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038448509293,"sku":"pro-1586-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-fetuin-b-bhp11004064","provider":"BioHippo","version":"1.0","type":"link"}