{"product_id":"recombinant-human-growth-and-differentiation-factor-15-d-vairant-bhp11000388","title":"Recombinant Human Growth and Differentiation factor 15 D-Vairant","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Growth and Differentiation factor 15 D-Vairant\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eGDF15 is part of the TGF-Beta superfamily that is involved in regulating inflammatory and apoptotic pathways in injured tissues and throughout disease processes. GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF-15 promotes proliferation or growth arrest and differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt and inhibiting endogenously active ERK. GDF15 is a novel autocrine\/endocrine factor that antagonizes the hypertrophic response and loss of ventricular performance.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038049460589,"sku":"cyt-314-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038282441069,"sku":"cyt-314-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038282473837,"sku":"cyt-314-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-gdf15-d-human-CYT-314.png?v=1782158131","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-growth-and-differentiation-factor-15-d-vairant-bhp11000388","provider":"BioHippo","version":"1.0","type":"link"}