{"product_id":"recombinant-human-growth-arrest-and-dna-damage-inducible-alpha-bhp11003258","title":"Recombinant Human Growth Arrest and DNA-Damage-Inducible Alpha","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Growth Arrest and DNA-Damage-Inducible Alpha\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eGrowth arrest and DNA Damage-Inducible Protein (GADD45A) binds both Cdks and PCNA. GADD45A is involved in DNA replication and repair. GADD45A stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A may serve as a link between p53-dependent cell cycle checkpoint and DNA repair. The GADD45A gene belongs to a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. GADD45A responds to environmental stresses by mediating activation of the p38\/JNK pathway via MTK1\/MEKK4 kinase. GADD45A binds to proliferating cell nuclear antigen.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038106313069,"sku":"pro-783-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038395490669,"sku":"pro-783-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038395523437,"sku":"pro-783-1MG","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-gadd45a-human-PRO-783.png?v=1782158248","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-growth-arrest-and-dna-damage-inducible-alpha-bhp11003258","provider":"BioHippo","version":"1.0","type":"link"}