{"product_id":"recombinant-human-guanine-nucleotide-binding-protein-beta-polypeptide-3-bhp11003424","title":"Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eGNB3 belongs to the WD repeat G protein beta family. GNB3 is an important regulator of alpha subunit, as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in GNB3 is linked with essential hypertension and obesity. In addition, this polymorphism is also linked with the occurrence of the splice variant GNB3-s, which seems to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Further splice variants may exist for GNB3, however they have not been fully described. Among the diseases associated with GNB3 are syncope, and aortic coarctation.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038112047469,"sku":"pro-332-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038405517677,"sku":"pro-332-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038405550445,"sku":"pro-332-1MG","price":3600.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-gnb3-human-PRO-332.png?v=1782158261","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-guanine-nucleotide-binding-protein-beta-polypeptide-3-bhp11003424","provider":"BioHippo","version":"1.0","type":"link"}