{"product_id":"recombinant-human-guanine-nucleotide-binding-protein-bhp11004279","title":"Recombinant Human Guanine Nucleotide Binding Protein","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Guanine Nucleotide Binding Protein\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eGNAQ, also known as Guanine nucleotide-binding protein belong to the G-alpha family. Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in a variety of transmembrane signaling systems. GNAQ regulates B-cell selection and survival and is essential in order to prevent B-cell-dependent autoimmunity. GNAQ also regulates chemotaxis of BM-derived neutrophils and dendritic cells, in vitro. GNAQ is an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been connected with problems in platelet activation and aggregation. A related pseudogene to GNAQ exists on chromosome 2 .\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038141866349,"sku":"pro-2070-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038463156589,"sku":"pro-2070-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038463189357,"sku":"pro-2070-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-gnaq-human-PRO-2070.png?v=1782158316","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-guanine-nucleotide-binding-protein-bhp11004279","provider":"BioHippo","version":"1.0","type":"link"}