{"product_id":"recombinant-human-hairy-and-enhancer-of-split-2-bhp11003427","title":"Recombinant Human Hairy and Enhancer of Split 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Hairy and Enhancer of Split 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eHairy and enhancer of split 2 (HES2) belongs to the HES family and comprised of one basic helix-loop-helix (bHLH) domain and one orange domain. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. Activation of Notch signaling pathway initiates activation of HES family genes throughout the interaction between Notch intracellular domain and RBPSUH (CSL). HES2 is expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038112211309,"sku":"pro-1649-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038406304109,"sku":"pro-1649-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038406336877,"sku":"pro-1649-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-hes2-human-PRO-1649.png?v=1782158260","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-hairy-and-enhancer-of-split-2-bhp11003427","provider":"BioHippo","version":"1.0","type":"link"}