{"product_id":"recombinant-human-inhibitor-of-growth-family-member-2-bhp11003551","title":"Recombinant Human Inhibitor of Growth Family, Member 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Inhibitor of Growth Family, Member 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eInhibitor of Growth Family, Member 2 (ING2) belongs to the inhibitor of growth (ING) family. ING family members associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and serve in DNA repair and apoptosis. ING2 appears to be involved in p53\/TP53 activation and p53\/TP53-dependent apoptotic pathways, most likely by enhancing acetylation of p53\/TP53. ING2 is a component of an mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity is modulated by binding to phosphoinositides (PtdInsPs).\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038117159277,"sku":"pro-1739-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038413775213,"sku":"pro-1739-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038413807981,"sku":"pro-1739-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-ing2-human-PRO-1739.png?v=1782158269","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-inhibitor-of-growth-family-member-2-bhp11003551","provider":"BioHippo","version":"1.0","type":"link"}