{"product_id":"recombinant-human-insulin-like-growth-factor-binding-protein-4-sf9-bhp11005846","title":"Recombinant Human Insulin Like Growth Factor Binding Protein-4, Sf9","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Insulin Like Growth Factor Binding Protein-4, Sf9\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eInsulin-like growth factor-binding protein 4 (IGFBP-4) is a part of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 includes an IGFBP domain and a thyroglobulin type-I domain. IGFBP4 binds both insulin-like growth factors (IGFs) I and II. IGFBP-4 circulates in the plasma in both glycosylated and non-glycosylated forms. IGFBPs can either inhibit or enhance the biological activities of IGF, or act in an IGF independent manner. IGFBP-4 is consistently inhibits several cancer cells in vivo and in vitro, suggesting that it may function as an apoptotic factor. IGFBP4 is produced by all colon cancer cells. Binding of IGFBP-4 prolongs the half-life of the IGFs and changes their interaction with cell surface receptors.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038175125869,"sku":"cyt-1114-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038530134381,"sku":"cyt-1114-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":53038530167149,"sku":"cyt-1114-01MG","price":765.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-igfbp4-protein-CYT-1114.png?v=1782158382","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-insulin-like-growth-factor-binding-protein-4-sf9-bhp11005846","provider":"BioHippo","version":"1.0","type":"link"}