{"product_id":"recombinant-human-interleukin-10-receptor-beta-bhp11000524","title":"Recombinant Human Interleukin 10 Receptor Beta","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Interleukin 10 Receptor Beta\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eIL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038054441325,"sku":"cyt-1025-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038290534765,"sku":"cyt-1025-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038290567533,"sku":"cyt-1025-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-il10-receptor-beta-CYT-1025.png?v=1782158137","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-interleukin-10-receptor-beta-bhp11000524","provider":"BioHippo","version":"1.0","type":"link"}