{"product_id":"recombinant-human-interleukin-37-bhp11000498","title":"Recombinant Human Interleukin 37","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Interleukin 37\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eHuman interleukin family 1, member 7 (IL1F7) belongs to the interleukin 1 cytokine family. There are 5 alternatively spliced transcript variants encoding distinct isoforms with distinct expression profiles. The longest IL-1F7 transcript, named IL1F7b or IL1F7 isoform 1, encodes a 218 aa residues proprotein and containing a 45 aa propeptide which is cleaved to produce a mature protein. IL1F7b binds to IL18 Rb with low affinity however it doesn’t exert any IL18 agonistic or antagonistic effects. IL1F7b also binds IL18BP (interleukin 18 binding protein), which is an inhibitory binding protein of interleukin 18 (IL18), and afterward forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"3 x 2 ug","offer_id":53038053196141,"sku":"cyt-011-3X2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038289158509,"sku":"cyt-011-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038289191277,"sku":"cyt-011-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-il1f7-human-CYT-011.png?v=1782158134","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-interleukin-37-bhp11000498","provider":"BioHippo","version":"1.0","type":"link"}