{"product_id":"recombinant-human-lsm1-homolog-u6-small-nuclear-rna-associated-bhp11005086","title":"Recombinant Human LSM1 Homolog, U6 Small Nuclear RNA Associated","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human LSM1 Homolog, U6 Small Nuclear RNA Associated\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eU6 snRNA-associated Sm-like protein LSm1 (LSM1) has a role in replication-dependent histone mRNA degradation and binds specifically to the 3''-terminal U-tract of U6 snRNA. Sm-like proteins include the Sm sequence motif, which consists of two regions separated by a linker of variable length that folds as a loop. The LSM1 protein facilitates RNA protein interactions and structural modifications which are required during ribosomal subunit assembly. The Sm-like proteins are believed to form a stable heteromer present in tri-snRNP particles, which are vital for pre-mRNA splicing. LSM1 is overexpressed in pancreatic cancer as well as in several breast cancer cell lines.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038167097709,"sku":"pro-259-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038512898413,"sku":"pro-259-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038512931181,"sku":"pro-259-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-lsm1-human-PRO-259.png?v=1782158364","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-lsm1-homolog-u6-small-nuclear-rna-associated-bhp11005086","provider":"BioHippo","version":"1.0","type":"link"}