{"product_id":"recombinant-human-lymphatic-vessel-endothelial-hyaluronic-acid-receptor-1-bhp11001322","title":"Recombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eLYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038067319149,"sku":"pka-250-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038317044077,"sku":"pka-250-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038317076845,"sku":"pka-250-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-lyve1-human-sf9-PKA-250.png?v=1782158165","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-lymphatic-vessel-endothelial-hyaluronic-acid-receptor-1-bhp11001322","provider":"BioHippo","version":"1.0","type":"link"}