{"product_id":"recombinant-human-met-proto-oncogene-bhp11003695","title":"Recombinant Human Met Proto-Oncogene","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Met Proto-Oncogene\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eMesenchymal epithelial transition factor (c-MET) is a proto-oncogenic receptor tyrosine kinase. The endogenous ligand for c-MET is HGF (hepatocyte growth factor), which is a disulfide-linked heterodimeric molecule produced predominantly by mesenchymal cells. In the adult, c-MET protein expression is limited to stem and progenitor cells and is required for wound healing and hepatocyte regeneration. In the embryo, c-MET receptors are expressed on cells of epithelial origin, which are vital for invasive growth and mediate epithelial-mesenchymal transition (EMT). Abnormal activation of the HGF\/MET pathway leads to a variety of cancers. c-MET mutation is linked with a poor prognosis since it can trigger tumor growth, angiogenesis and metastasis.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038121877869,"sku":"pro-207-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038423343469,"sku":"pro-207-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038423376237,"sku":"pro-207-100UG","price":1000.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-met-human-PRO-207.png?v=1782158278","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-met-proto-oncogene-bhp11003695","provider":"BioHippo","version":"1.0","type":"link"}