{"product_id":"recombinant-human-mothers-against-decapentaplegic-homolog-4-bhp11004889","title":"Recombinant Human Mothers Against Decapentaplegic Homolog 4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Mothers Against Decapentaplegic Homolog 4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eSMAD4 is part of the SMAD family of proteins that mediate signal transduction by the TGF-beta\/activin\/BMP-2\/4 cytokine superfamily from receptor Ser\/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2\/SMAD4\/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription acts as a tumor suppressor. SMAD4 is a target molecule for functional inactivation in cervical cancer. SMAD4 is an important biomarker for malignant transformation atakes part in inducing apoptosis by modulating Bcl-2\/Bax balance.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10 ug","offer_id":53038161756525,"sku":"pro-459-10UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038500184429,"sku":"pro-459-50UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038500217197,"sku":"pro-459-1MG","price":1800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-smad4-human-PRO-459.png?v=1782158353","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-mothers-against-decapentaplegic-homolog-4-bhp11004889","provider":"BioHippo","version":"1.0","type":"link"}