{"product_id":"recombinant-human-muts-homolog-6-bhp11004516","title":"Recombinant Human MutS Homolog 6","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human MutS Homolog 6\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eMSH6 deficiency result in hereditary non-polyposis colorectal cancer (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease linked with rise in cancer susceptibility. MSH6 is is known by its familial predisposition to premature onset colorectal carcinoma (crc). MSH6 is involved in repairing DNA. MSH6 protein repairs mistakes that occure during DNA replication in preparation for cell division. The MSH6 protein bonds with MSH2 protein and form an active protein complex which recognizes specific parts on the DNA where mistakes have been made during DNA replication. MLH1-PMS2 protein complex, afterwards takes over with the repair. MSH6 gene is part of the set of the mismatch repair (MMR) genes.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038149894509,"sku":"pro-745-2UG","price":175.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038478229869,"sku":"pro-745-5UG","price":270.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038478262637,"sku":"pro-745-10UG","price":490.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-msh6-human-PRO-745.png?v=1782158331","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-muts-homolog-6-bhp11004516","provider":"BioHippo","version":"1.0","type":"link"}