{"product_id":"recombinant-human-nonhomologous-end-joining-factor-1-bhp11003898","title":"Recombinant Human Nonhomologous End-Joining Factor 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Nonhomologous End-Joining Factor 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eNon-homologous end-joining factor 1 (NHEJ1) is a member of the XLF family. NHEJ1 is a DNA repair factor vital for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. NHEJ1 gene mutations cause different kinds of severe combined immunodeficiency disorders. NHEJ1 was initially detected as the protein mutated in five patients with growth retardation, microcephaly, and immunodeficiency. In addition, patients with NHEJ1 mutations have immunodeficiency caused by a defect in V(D)J recombination, which employs NHEJ to promote immune system diversity.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038129512813,"sku":"pro-1193-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038436286829,"sku":"pro-1193-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038436319597,"sku":"pro-1193-100UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-nhej1-human-PRO-1193.png?v=1782158293","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-nonhomologous-end-joining-factor-1-bhp11003898","provider":"BioHippo","version":"1.0","type":"link"}