{"product_id":"recombinant-human-nuclear-factor-of-activated-t-cells-2-bhp11005760","title":"Recombinant Human Nuclear Factor Of Activated T Cells 2","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Nuclear Factor Of Activated T Cells 2\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eNFATC2, also known as nuclear factor of activated T-cells 2, belongs to the nuclear factor of activated T cells family. NFATC2 takes a significant part in the course of T helper cell differentiation, activation, and effector function. Even though KO of an individual NFAT isoform in T cells directs to rather minor effects, T cells lacking for NFATC1 and 2 totally fail to produce T helper cell effector cytokines, for instance the interleukins IL-4 and IL-2. Moreover, NFATC2 is highly phosphorylated and kept in the cytoplasm. Next T cell receptor stimulation, dephosphorylation via calcium-activated calcineurin induces a conformational modification of NFATC2 which reveals a few nuclear localization sequences.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038173028717,"sku":"pro-2535-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038526333293,"sku":"pro-2535-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038526366061,"sku":"pro-2535-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-nfatc2-human-PRO-2535.png?v=1782158377","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-nuclear-factor-of-activated-t-cells-2-bhp11005760","provider":"BioHippo","version":"1.0","type":"link"}