{"product_id":"recombinant-human-nucleic-acid-binding-protein-1-bhp11004115","title":"Recombinant Human Nucleic Acid Binding Protein 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Nucleic Acid Binding Protein 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eNucleic acid binding protein 1 is a part of the SOSS complex, a multiprotein complex which functions downstream of the MRN complex to promote DNA repair and G2\/M checkpoint . In the SOSS complex, NABP1 acts as a sensor of single-stranded DNA which binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex links with DNA lesions and affects diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. NABP1 is essential for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways .\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038135935341,"sku":"pro-1718-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038452703597,"sku":"pro-1718-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038452736365,"sku":"pro-1718-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-nabp1-human-PRO-1718.png?v=1782158307","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-nucleic-acid-binding-protein-1-bhp11004115","provider":"BioHippo","version":"1.0","type":"link"}