{"product_id":"recombinant-human-par-6-partitioning-defective-6-homolog-beta-bhp11003944","title":"Recombinant Human Par-6 Partitioning Defective 6 Homolog Beta","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Par-6 Partitioning Defective 6 Homolog Beta\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003ePartitioning defective 6 homolog beta (PARD6B) belongs to the PAR6 family and encodes a protein with a PSD95\/Discs-large\/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42\/Rac interactive binding (CRIB) domain. Cellular asymmetry is crucial for the development of multicellular organisms. PARD (partitioning-defective) proteins have central roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. PARD6B is expressed in pancreas and in both the adult and the fetal kidney, and is weakly expressed in the placenta and the lung.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038130921837,"sku":"pro-1307-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038439793005,"sku":"pro-1307-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038439825773,"sku":"pro-1307-100UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-pard6b-human-PRO-1307.png?v=1782158296","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-par-6-partitioning-defective-6-homolog-beta-bhp11003944","provider":"BioHippo","version":"1.0","type":"link"}