{"product_id":"recombinant-human-proliferating-cell-antigen-bhp11004596","title":"Recombinant Human Proliferating Cell Antigen","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Proliferating Cell Antigen\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003ePCNA is located in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated and takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 and on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis and persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038151598445,"sku":"pro-615-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038482948461,"sku":"pro-615-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038482981229,"sku":"pro-615-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-proliferating-cell-antigen-bhp11004596","provider":"BioHippo","version":"1.0","type":"link"}