{"product_id":"recombinant-human-rh-blood-group-d-antigen-bhp11006527","title":"Recombinant Human Rh Blood Group D Antigen","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Rh Blood Group D Antigen\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eThe Rh blood group system is one of the major blood group systems in humans and the D antigen is the main component of this system. D Antigen The presence of the D antigen on the surface of red blood cells indicates a positive Rh factor. Individuals with this antigen are classified as Rh-positive (Rh+), while those without it are Rh-negative (Rh-). Genetics The Rh factor is inherited in a Mendelian manner, with the D antigen being monitored by the RHD gene located on chromosome\u003cbr\u003e1. The presence of the D allele (RHD) results in Rh positivity. Immunization Rh-negative individuals can develop antibodies against the D antigen if exposed to Rh-positive blood. In order to prevent such interaction, Rh-negative mothers are often given Rh immunoglobulin (Rho(D) immune globulin) during and after pregnancy. Clinical Significance The Rh D antigen is vital in blood transfusions and pregnancy. Rh incompatibility can occur when an Rh- mother carries an Rh+ fetus, which may lead to hemolytic disease of the newborn (HDN). Blood Transfusions Rh compatibility is very important in transfusions. Rh- individuals should receive Rh- blood to avoid an immune reaction.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"50 ug","offer_id":53038190002541,"sku":"pro-2822-50UG","price":200.0,"currency_code":"USD","in_stock":true},{"title":"100 ug","offer_id":53038566506861,"sku":"pro-2822-100UG","price":300.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038566539629,"sku":"pro-2822-1MG","price":1500.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-rhd-human-PRO-2822.png?v=1782158407","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-rh-blood-group-d-antigen-bhp11006527","provider":"BioHippo","version":"1.0","type":"link"}