{"product_id":"recombinant-human-s-phase-kinase-associated-protein-1-isoform-a-bhp11001778","title":"Recombinant Human S-phase Kinase-Associated Protein 1 Isoform A","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human S-phase Kinase-Associated Protein 1 Isoform A\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eSKP1 is a F-box enzyme which functions as a substrate recognition component of the SCF ubiquitin ligase complex which controls the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SKP1 binds to proteins containing an F-box motif, such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. SKP1 takes part in the control of beta-catenin levels and the activity of beta-catenin dependent TCF transcription factors. SKP1 serves as an adapter that links the F-box protein to CUL1 in the SCF complex.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038070956397,"sku":"pka-356-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"25 ug","offer_id":53038325498221,"sku":"pka-356-25UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038325530989,"sku":"pka-356-1MG","price":2250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-skp1-human-PKA-356.png?v=1782158172","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-s-phase-kinase-associated-protein-1-isoform-a-bhp11001778","provider":"BioHippo","version":"1.0","type":"link"}