{"product_id":"recombinant-human-small-nuclear-ribonucleoprotein-polypeptide-a-bhp11004897","title":"Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Small Nuclear Ribonucleoprotein Polypeptide A\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eSNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4\/U6\/U5 tri-snRNP.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038161363309,"sku":"pro-1509-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038501101933,"sku":"pro-1509-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038501134701,"sku":"pro-1509-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-snrpa-human-PRO-1509.png?v=1782158352","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-small-nuclear-ribonucleoprotein-polypeptide-a-bhp11004897","provider":"BioHippo","version":"1.0","type":"link"}