{"product_id":"recombinant-human-smarca4-bhp11004280","title":"Recombinant Human SMARCA4","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human SMARCA4\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eSMARCA4 belongs to the SWI\/SNF family of proteins and is similar to the brahma protein of Drosophila. Proteins in this family have helicase and ATPase activities and are considered to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA4 is part of the large ATP - dependent chromatin remodeling complex SNF\/SWI, which is essential for transcriptional activation of genes normally repressed by chromatin. In addition, SMARCA4 is able to bind BRCA1, as well as regulating the expression of the tumorigenic protein CD44. Moreover, mutations in SMARCA4 cause rhabdoid tumor predisposition syndrome type 2 .\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038140850541,"sku":"pro-2071-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038463418733,"sku":"pro-2071-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038463451501,"sku":"pro-2071-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-smarca4-human-PRO-2071.png?v=1782158318","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-smarca4-bhp11004280","provider":"BioHippo","version":"1.0","type":"link"}