{"product_id":"recombinant-human-soluble-cd40-ligand-trap-bhp11000120","title":"Recombinant Human soluble CD40 Ligand\/TRAP","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human soluble CD40 Ligand\/TRAP\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eCD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines . CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma , TNF-alpha , and IL2 .\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e\n\u003ch3\u003eQuality notes\u003c\/h3\u003e\n\u003cp\u003eProtein quantitation was carried out by two independent methods:\u003cbr\u003e1. UV spectroscopy at 280 nm using the absorbency value of 1.1 as the extinction coefficient for a 0.1% (1mg\/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).\u003cbr\u003e2. Analysis by RP-HPLC, using a standard solution of CD40 as a Reference Standard.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10 ug","offer_id":53038045921645,"sku":"cyt-245-10UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038268940653,"sku":"cyt-245-50UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038268973421,"sku":"cyt-245-1MG","price":1350.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-cd40-human-CYT-245.png?v=1782158118","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-soluble-cd40-ligand-trap-bhp11000120","provider":"BioHippo","version":"1.0","type":"link"}