{"product_id":"recombinant-human-soluble-rank-ligand-gst-tag-bhp11002510","title":"Recombinant Human Soluble RANK Ligand, GST Tag","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Soluble RANK Ligand, GST Tag\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eRANKL binds to tnfrsf11b\/opg and to tnfrsf11a\/rank. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive t-cell proliferation. May be an important regulator of interactions between t-cells and dendritic cells and may play a role in the regulation of the t-cell-dependent immune response. sRANKL may also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. By injecting soluble RANKL, novel osteopenia model mice were established in only 50 hours. Degree of bone loss can be controlled by changing doses of sRANKL. RANKL can be used in establishing osteopenia model for in vivo screening of drugs for osteoporosis, determination of effect and mechanism, evaluation of bone anabolic drugs.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038082752877,"sku":"cyt-631-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038348861805,"sku":"cyt-631-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"0.1 mg","offer_id":53038348894573,"sku":"cyt-631-01MG","price":1100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-rankl-human-gst-CYT-631.png?v=1782158199","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-soluble-rank-ligand-gst-tag-bhp11002510","provider":"BioHippo","version":"1.0","type":"link"}