{"product_id":"recombinant-human-son-of-sevenless-homolog-1-bhp11004419","title":"Recombinant Human Son Of Sevenless Homolog 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Son Of Sevenless Homolog 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eSOS1, also known as Gingival Fibromatosis, is a Ras \u0026amp; Rac guanine nucleotide exchange factor. SOS1 is comprised of a number of significant domains. The REM and CDC25 domains provide the catalytic activity of SOS1 towards Ras and the histone fold DH\/PH (Dbl homology \u0026amp; Pleckstrin homology) domains function, in tandem, to stimulate GTP\/GDP exchange for Rac. Moreover, binding of GTP activates Ras proteins, and subsequent hydrolysis of the bound GTP to GDP and phosphate inactivates signaling by these proteins. GTP binding can be catalyzed by guanine nucleotide exchange factors for RAS, and GTP hydrolysis can be enhanced by GTPase-activating proteins.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038146093421,"sku":"pro-2507-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038471774573,"sku":"pro-2507-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038471807341,"sku":"pro-2507-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-sos1-human-PRO-2507.png?v=1782158326","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-son-of-sevenless-homolog-1-bhp11004419","provider":"BioHippo","version":"1.0","type":"link"}