{"product_id":"recombinant-human-tar-dna-binding-protein-1-414-a-a-bhp11005006","title":"Recombinant Human TAR DNA Binding Protein, (1-414 a.a.)","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human TAR DNA Binding Protein, (1-414 a.a.)\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTAR DNA Binding Protein (TARDBP) was initially recognized as a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP has been detected in individuals diagnosed with chronic traumatic encephalopathy as well, which is a condition that often imitates ALS and has been related with athletes who have experienced multiple concussions and other types of head injury . TARDBP has been shown to bind both DNA and RNA, it has multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation .\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038164017517,"sku":"pro-2383-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038507589997,"sku":"pro-2383-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038507622765,"sku":"pro-2383-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-human-tardbp-1-414-PRO-2383.png?v=1782158359","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-tar-dna-binding-protein-1-414-a-a-bhp11005006","provider":"BioHippo","version":"1.0","type":"link"}