{"product_id":"recombinant-human-tar-dna-binding-protein-his-tag-1-414-a-a-bhp11005004","title":"Recombinant Human TAR DNA Binding Protein, His Tag (1-414 a.a.)","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human TAR DNA Binding Protein, His Tag (1-414 a.a.)\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTAR DNA Binding Protein (TARDBP) was initially recognized as a transcriptional repressor which binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, TARDBP has been detected in individuals diagnosed with chronic traumatic encephalopathy as well, which is a condition that often imitates ALS and has been related with athletes who have experienced multiple concussions and other types of head injury . TARDBP has been shown to bind both DNA and RNA, it has multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation .\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038164312429,"sku":"pro-1459-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038507393389,"sku":"pro-1459-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038507426157,"sku":"pro-1459-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-tardbp-1-414-human-PRO-1459.png?v=1782158359","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-tar-dna-binding-protein-his-tag-1-414-a-a-bhp11005004","provider":"BioHippo","version":"1.0","type":"link"}