{"product_id":"recombinant-human-toll-interleukin-1-receptor-tir-domain-containing-adaptor-protein-bhp11003892","title":"Recombinant Human Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eToll-interleukin1 receptor (TIR) domain containing adaptor protein (TIRAP) contains 1 TIR domain. TIRAP is an adapter molecule linked with toll-like receptors. TIRAP is required in TLR2 and TLR4 signaling pathways in the innate immune response. TIRAP activates NF-kappa-B, MAPK1, MAPK3 and JNK, which subsequently results in cytokine secretion and the inflammatory response. TIRAP is highly expressed in the liver, kidney, spleen, skeletal muscle and heart. TIRAP is also found in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038128988525,"sku":"pro-1181-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038435828077,"sku":"pro-1181-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038435860845,"sku":"pro-1181-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-tirap-human-PRO-1181.png?v=1782158291","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-toll-interleukin-1-receptor-tir-domain-containing-adaptor-protein-bhp11003892","provider":"BioHippo","version":"1.0","type":"link"}