{"product_id":"recombinant-human-toll-like-receptor-3-bhp11005034","title":"Recombinant Human Toll Like Receptor 3","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human Toll Like Receptor 3\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTLR3 (Toll-like receptor 3) belongs to the toll-like receptor family which takes an essential part in pathogen recognition as well as activation of innate immunity. TLR3 has innate immune receptors for sensing microbial molecules in addition to damage-associated molecular patterns released from host cells. TLR3 recognizes dsRNA and activation of the receptor which induces the activation of NF-kappaB and the production of type I interferons. TLR3 signaling activation is related with ischemic preconditioning-induced protection against brain ischemia and attenuation of reactive astrogliosis. TLR3 is most plentifully expressed in the placenta \u0026amp; pancreas, and is limited to the dendritic subpopulation of the leukocytes.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"1 ug","offer_id":53038164967789,"sku":"pro-2511-1UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"5 ug","offer_id":53038510473581,"sku":"pro-2511-5UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038510506349,"sku":"pro-2511-50UG","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-tlr3-human-PRO-2511.png?v=1782158359","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-toll-like-receptor-3-bhp11005034","provider":"BioHippo","version":"1.0","type":"link"}