{"product_id":"recombinant-human-tp53-regulated-inhibitor-of-apoptosis-1-bhp11004141","title":"Recombinant Human TP53 Regulated Inhibitor Of Apoptosis 1","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human TP53 Regulated Inhibitor Of Apoptosis 1\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTRIAP1 has a p53-binding site in its second exon. TRIAP1 expression is reduced by small interfering RNA enhanced apoptosis, while overexpression of TRIAP1 protects cells from apoptosis triggered by DNA damage. TRIAP1 is highly induced when cells have low levels of genotoxic stresses, but not when DNA damage is severe. TRIAP1 is able to control apoptotic pathways by interacting with Hsp70 which inhibits activity of apoptosis protease activating factor-1.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"5 ug","offer_id":53038136623469,"sku":"pro-1771-5UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"20 ug","offer_id":53038454735213,"sku":"pro-1771-20UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038454767981,"sku":"pro-1771-1MG","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-triap1-human-PRO-1771.png?v=1782158311","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-tp53-regulated-inhibitor-of-apoptosis-1-bhp11004141","provider":"BioHippo","version":"1.0","type":"link"}