{"product_id":"recombinant-human-traf-family-member-associated-nfkb-activator-1-119-a-a-bhp11005032","title":"Recombinant Human TRAF Family Member-Associated NFKB Activator, (1-119 a.a.)","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human TRAF Family Member-Associated NFKB Activator, (1-119 a.a.)\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTRAF2 protein is related with transduce signals from members of the TNFR superfamily. TRAF2 is located in the cytoplasm binds to TRAF1, TRAF2, or TRAF3, thus inhibiting TRAF function by sequestering the TRAFs in a suppressed state in the cytoplasm. Overexpression of TANK inhibits TRAF2-mediated NF-Kappa-B activation signaled by CD40 and both TNF receptors and inhibits LMP1-mediated NF-kappa-B activation by blocking the association of TRAF2 with LMP1. TRAF2 is necessary for the cellular response to TNF-alpha by connecting upstream signalling molecules to the IKKs and p65.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"10 ug","offer_id":53038165492077,"sku":"pro-685-10UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"50 ug","offer_id":53038509818221,"sku":"pro-685-50UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038509850989,"sku":"pro-685-1MG","price":2400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-traf2-human-PRO-685.png?v=1782158360","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-traf-family-member-associated-nfkb-activator-1-119-a-a-bhp11005032","provider":"BioHippo","version":"1.0","type":"link"}