{"product_id":"recombinant-human-traf-interacting-protein-with-forkhead-associated-domain-bhp11003849","title":"Recombinant Human TRAF-Interacting Protein with Forkhead-Associated Domain","description":"\u003cp\u003e\u003cstrong\u003eRecombinant Human TRAF-Interacting Protein with Forkhead-Associated Domain\u003c\/strong\u003e is supplied as a recombinant protein for in vitro research use.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\n\u003cp\u003eTRAF-interacting protein with FHA domain-containing protein A (TIFA) is an adapter protein that mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, triggering the downstream activation of NF-kappa-B and AP-1 pathways. The TIFA protein stimulates the oligomerization and polyubiquitination of TRAF6, leading to the activation of TAK1 and IKK through a proteasome-independent mechanism.\u003c\/p\u003e\n\u003ch3\u003eProduct format\u003c\/h3\u003e\n\u003cp\u003eProvided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.\u003c\/p\u003e","brand":"ProSpec-Tany TechnoGene Ltd","offers":[{"title":"2 ug","offer_id":53038127972717,"sku":"pro-1041-2UG","price":60.0,"currency_code":"USD","in_stock":true},{"title":"10 ug","offer_id":53038433272173,"sku":"pro-1041-10UG","price":145.0,"currency_code":"USD","in_stock":true},{"title":"1 mg","offer_id":53038433304941,"sku":"pro-1041-1MG","price":5200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0949\/7424\/7277\/files\/Prospecbio-tifa-human-PRO-1041.png?v=1782158290","url":"https:\/\/www.ebiohippo.com\/products\/recombinant-human-traf-interacting-protein-with-forkhead-associated-domain-bhp11003849","provider":"BioHippo","version":"1.0","type":"link"}